Eastern Mediterranean Cruise: How Does It Compare To A Western Mediterranean Cruise?

Set sail on Mediterranean cruise to visit the Eastern Mediterranean and Western Mediterranean favorite destinations.

An Eastern Mediterranean cruise offers a perfect blend of ancient history, breathtaking landscapes, and warm hospitality. Meanwhile, a Western Mediterranean cruise enchants travelers with its cosmopolitan cities, coastal villages, and rich cultural heritage. Together, these regions create an unforgettable voyage filled with diverse experiences waiting at every port. Whether you’re a history buff, a foodie, or an adventurer, there’s something for everyone in these Mediterranean gems.

Discover the wonders on an Eastern Mediterranean cruise

Visit Santorini, Greece on your cruise to the Eastern Mediterranean.

The destinations on an Eastern Mediterranean cruise are a treasure trove of ancient ruins, lively markets, and stunning seascapes. Start your adventure in Santorini, Greece. This iconic island enchants visitors with its whitewashed houses, blue-domed churches, and views of the sparkling Aegean Sea. Explore Oia’s narrow streets, indulge in freshly caught seafood, and don’t miss a sunset that lights up the sky in hues of orange and pink.

Another must-see is Dubrovnik, Croatia, also known as the “Pearl of the Adriatic.” Walk Croatia’s ancient city walls and take in panoramic views of the orange rooftops and the cobalt-blue sea. For history lovers, Dubrovnik’s Old Town is a UNESCO World Heritage Site brimming with Gothic and Baroque monuments. Activities such as kayaking along the coastline or enjoying local wines complete the visit.

Cruise lines like Celebrity Cruises and Norwegian Cruise Line offer itineraries featuring these incredible destinations. While onboard, enjoy luxurious amenities before stepping ashore to become part of the adventure.

Cultural treasures of a Western Mediterranean cruise

Visit Italy's Amalfi Coast on your cruise to the Western Mediterranean.

A Western Mediterranean cruise caters to those seeking charm and elegance intertwined with history and art. One standout destination is Barcelona, Spain. This bustling city is famous for Antonio Gaudí’s stunning architecture, like the Sagrada Família and Park Güell. Spend your day admiring these whimsical structures, tasting tapas in a local eatery, and savoring cava, a sparkling Spanish wine.

Italy’s Amalfi Coast is another highlight, where dramatic cliffs meet crystal-clear waters. Visit towns like Positano or Ravello, known for their romantic settings and artistic history. Try the region’s famous limoncello or relax with a leisurely boat ride along the coastline. It’s a slice of paradise that feels like stepping into a postcard.

Major cruise lines like MSC Cruises and Princess Cruises often include Barcelona and the Amalfi Coast on their voyages, giving you the chance to explore these spots in depth.

Mediterranean islands bursting with beauty

Visit Palma de Mallorca on your cruise to the Eastern Mediterranean and Western Mediterranean.

Both the Eastern and Western Mediterranean cruises boast remarkable islands, each with its unique allure. In the East, Crete is Greece’s largest island. Rich in mythology and history, Crete offers gorgeous beaches, hiking trails in Samaria Gorge, and the Minoan palace of Knossos. Every corner of Crete reveals another layer of its fascinating past and stunning natural beauty.

On the Western side, Mallorca in Spain enchants visitors with its vibrant city of Palma and unspoiled beach coves. Stroll along the Paseo Marítimo, explore the grandeur of La Seu Cathedral, or hike through the Tramuntana mountains. Whether you prefer relaxation or adventure, Mallorca has something special.

Experiencing a Western or Eastern Mediterranean cruise your way

Visit Turkey on your cruise to the Eastern Mediterranean and Western Mediterranean.

An Eastern Mediterranean cruise lets you immerse yourself in regions steeped in history and unmistakable charm. Marvel at Grecian ruins or wander through bazaars in Turkey. Meanwhile, a Western Mediterranean voyage reveals glamorous cities like Monaco or serene spots like Provence. Both regions promise indulgence, exploration, and countless photo-worthy moments.

For a seamless experience, many cruise lines, including Oceania Cruises and Azamara, focus on smaller, more intimate journeys through hidden gems in each region. You’ll have the chance to enjoy uncrowded islands and connect deeply with each destination.


Ready to book your dream adventure to the Mediterranean? Discover all the Europe cruises at Cruises.com.

Set sail with Cruises.com Rewards! Unlock exclusive member-only pricing and earn 10 points per $1 on every booking. Earn twice by stacking your savings with your cruise line loyalty status and perks! Redeem your rewards for cash on the same upcoming cruise. Let’s book your next adventure — and make it more rewarding! Join Cruises.com Rewards for free today. Book your dream vacation now or call us at 800-288-6006 start earning.

Related: Mediterranean Cruises: Top Ports to Explore